NFL Week 4 Betting Guide

Story posted September 30, 2022 in

The following article contains information that is not representative of the opinions of CommRadio. It solely expresses the opinions of Joseph Granton.

After a wild NFL Week 3, we’re back with a Week 4 breakdown to put some serious money in your pocket.

Sunday, Oct. 2: Vikings @ Saints (+2.5, 43.5)

Our Sunday slate begins in London this week, as the 2-1 Vikings “host” the 1-2 Saints.

New Orleans will be limping into Tottenham Hotspur Stadium, as they will be without wideout Michael

Thomas, safety Marcus Maye and most likely quarterback Jameis Winston. Also, the Saints are coming off back to back divisional losses, and I don’t see them picking up a win this week. 

Minnesota will cover -2.5 in a low-scoring, fast moving game that stays under 43.5.

Sunday, Oct. 2: Bills @ Ravens (+3, 51)

My favorite game of the week, with potential to be one of the best games of the year is the Bills (2-1) traveling to Baltimore to face the Ravens (2-1). Both of these teams are a once score loss from the Miami Dolphins away from being undefeated, but only one of these teams can be 3-1 after this week.

Buffalo remains riddled with injuries to the secondary, and will have to face the hottest player in the NFL right now in quarterback Lamar Jackson. However, Baltimore ranks dead last in pass defense, and has to face current MVP favorite, quarterback Josh Allen.

I believe this game will be extremely close, and come down to only a possession or two. With that being said, I’m going to have to back my preseason Super Bowl pick, and go with the Bills -3 in a game that will see some scoring, but ultimately stay under 51.

Sunday, Oct. 2 - Cardinals @ Panthers (+1.5, 43.5)

This Sunday’s “America’s Game of the Week” will take place in North Carolina, with the Cardinals (1-2) taking on the Panthers (1-2). Carolina comes into this week a team with little to no offensive identity, trailing only the Steelers and Bears in yards per game.

Also, Arizona is the best road team in the NFL, as they have gone 9-1 on the road since the beginning of 2021. Arizona’s defense has been a liability to start the season, but going against Baker Mayfield and the stifling Panthers offense, look for the Cardinals to advance to 2-2 after covering -1.5 in a game that goes over 43.5.

Sunday, Oct. 2: Chiefs @ Buccaneers (-1 , 45.5)

Sunday Night Football features a battle between quarterbacks Patrick Mahomes and Tom Brady. This is a matchup we have seen five times before, with Brady winning three of them.

Tampa Bay is dealing with injuries, especially to their offense, and it has shown, as they are tied for the second lowest touchdown total with four (one of which is a defensive touchdown). Kansas City on the other hand has barely missed a step on offense, as Mahomes has accounted for eight touchdowns by himself.

I expect Kansas City to totally dominate this game, as the Buccaneers injuries woes will be too much to overcome. Chiefs will cover +1, as well as win outright in a game that stays under 45.5 points. With that being said, don’t be surprised if Tom Brady resurrects this season and makes this game a shootout.

Monday, Oct. 3: Rams @ Niners (-1.5, 42.5)

ESPN gets to broadcast an absolute beauty for Monday Night Football, as divisional rivals Niners host the NFC West leading, defending Super Bowl Champion Rams.

Recently, this is a matchup that very much favors San Francisco, as the Niners have won six out of the last seven times these two teams have met. Yet, Los Angeles can still say they won the most important one, toppling the Niners in the 2022 NFC Championship game.

With that being said, I will stick with the trend of Niners over Rams, and I expect the Niners to cover -1.5 easily, dominating the clock in a very low scoring game that stays under 42.5.

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Joseph Granton is a second-year majoring in broadcast journalism. To contact him, please email

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